Teri Belecky-Adams, Ph.D.

Image of Dr. Belecky Adams

Center Director

Associate Professor of Biology

Departmentof Biology, School of Science

Indiana University-Purdue University Indianapolis

723 W. Michigan St.

Indianapolis, IN 46202

Phone: (317) 274-0627

Fax: (3127) 274-2846

Email: tbadams@iupui.edu

RESEARCH INTERESTS

The research of my laboratory involves several aspects of central nervous system development and regeneration:

    1) The study of inflammatory changes within the retina as a result of injury and/or disease and the potential outcome of chronic inflammation in triggering glial scarring.
    2) Identification of factors that are critical to the development of a cell type in the nervous system known as astrocytes.
    3) The role of epigenetics in retinal development and disease.
    4) The role of canonical and non-canonical bone morphogenetic signaling in retinal development and disease.

SELECTED RECENT PUBLICATIONS

    Tiwari, A, Dharmarajan, S, Shivanna, M, Otteson, DC, Belecky-Adams, TL (2014) Histone deacetylase expression patterns in developing murine optic nerve. BMC Dev Biol. 2014 Jul 9;14:30. doi: 10.1186/1471-213X-14-30. PMID:25011550.
    Dharmarajan, S, Gurel, Z, Wang, S, Sorenson, CM, Sheibani, N, Belecky-Adams, TL (2014) Bone morphogenetic protein 7 regulated reactive gliosis in retinal astrocytes and Müller glia. Mol Vis. 2014 Jul 31;20:1085-108. PMID 25253985.
    Rao N, Song F, Jhamb D, Wang M, Milner DJ, Price NM, Belecky-AdamsTL, Palakal MJ, Cameron JA, Li B, Chen X, Stocum DL. (2014) Proteomic analysis of fibroblastema formation in regenerating hindlimbs of Xenopus laevis froglets and comparison to axolotl. BMC Dev Biol. 2014 Jul 25;14:32. doi: 10.1186/1471-213X-14-32. PMID:25063185.
    Belecky-Adams, TL, Chernoff, EC, Wilson, JM, and Dharmarajan, S (2013). Reactive Müller glia as potential retinal progenitors. Neural Stem Cells: New Perspectives, ed. Luca Bonfanti, ISBN 978-953-51-1069-9, Publisher: InTech, pp 73-117.
    Tiwari, S., Hudson, S, Gattone, VH, Miller, C, Chernoff, EC, and Belecky-Adams, TL (2013) Meckelin 3 is necessary for photoreceptor outer segment development in rat Meckel Syndrome. PLOS One: ;8(3):e59306. doi: 10.1371/journal.pone.0059306
    Belecky-Adams, TL., Chernoff, EC, Wilson, JM, and Dharmarajan, S. (2013) Reactive Gliosis in Muller Glia: Potential Retinal Progenitors. Neural Stem Cells. Editor Luca Bonfanti, INTECH, pp 73-117.
    Belecky-Adams TL, Hudson SR, Tiwari S. (2012) In ovo eye electroporation. Methods Mol Biol. 2012;884:71-89. doi: 10.1007/978-1-61779-848-1_5.
    Wilson, JM, Martinez-DeLuna, R, El Hodiri, HM, Smith, R, King, MW, Mescher, AL, Neff, AW, and Belecky-Adams, TL. (2010) RNA helicase Ddx39 is a marker of proliferating cells in the developing and regenerating retina of Xenopus laevis. Gene Expr Patterns. Jan;10(1):44-52.
    Sehgal, R, Sheibani, N, Rhodes, SJ, Belecky-Adams, TL. (2009) BMP7 and SHH regulate Pax2 in retinal astrocytes by relieving TLX repression. Dev. Biol. 332: 429-443.
    Sehgal, R, Karcavich, R, Carlson, S, and Belecky-Adams, TL (2008) Ectopic PAX2 expression in the ventral optic cup phenocopies loss of PAX2 expression. Dev. Biol. 319:23-33.
    Wilson JM, Sato K, Chernoff EA, Belecky-Adams TL. (2007) Expression patterns of chick Musashi-1 in the developing nervous system. Gene Expr Patterns: 7(7):817-25.
    Sehgal R, Andres DJ, Adler R, Belecky-Adams TL. (2006) Bone morphogenetic protein 7 increases chick photoreceptor outer segment initiation. Invest Ophthalmol Vis Sci. 47(8):3625-34.
    Fong SL, Criswell MH, Belecky-Adams T, Fong WB, McClintick JN, Kao WW, Edenberg HJ. (2005) Characterization of a transgenic mouse line lacking photoreceptor development within the ventral retina. Exp Eye Res. 81(4):376-88.